Marijn van Jaarsveld | CARAMBA https://www.caramba-cart.eu CARAMBA Mon, 03 Jul 2023 07:23:07 +0000 en-US hourly 1 https://www.caramba-cart.eu/wp-content/uploads/2018/03/cropped-caramba-icon-512px-x-512px-32x32.png Marijn van Jaarsveld | CARAMBA https://www.caramba-cart.eu 32 32 Video interviews with CARAMBA researchers https://www.caramba-cart.eu/video-interviews-with-caramba-researchers/?utm_source=rss&utm_medium=rss&utm_campaign=video-interviews-with-caramba-researchers Fri, 30 Jun 2023 14:50:29 +0000 https://www.caramba-cart.eu/?p=5844
MPE’s video interviews with CARAMBA researchers

Myeloma Patients Europe conducted a series of interviews with CARAMBA researchers on the challenges of CAR T-cell therapy. Watch the videos below, produced by Myeloma Patients Europe. 

CARAMBA clinical trial updates on safety

Prof. Dr. Ibrahim Yakoub-Agha, Head of the Hematopoietic Cell Transplantation Unit at Lille University Hospital, explains the safety updates.

 

CARAMBA manufacturing process – Prof. Dr. Halvard Bönig

Prof. Dr. Halvard B. Bönig, Research and Development Department Translational Cell Therapy Development/GMP, explains the manufacturing process of the CARAMBA CAR-T treatment.

 

Immune Monitoring – Dr. Bruno Paiva

Dr. Bruno Paiva, Scientific Coordinator of the Diagnostic Laboratories of the University of Navarra (Spain), explains what immune monitoring is.

 

The post Video interviews with CARAMBA researchers first appeared on CARAMBA.]]> CARAMBA Meeting Report https://www.caramba-cart.eu/caramba-meeting-report/?utm_source=rss&utm_medium=rss&utm_campaign=caramba-meeting-report Fri, 30 Jun 2023 11:52:55 +0000 https://www.caramba-cart.eu/?p=5824 The CARAMBA project presents its experiences, lessons learned and achievements in the development of an innovative CAR T-cell therapy for Multiple Myeloma treatment Read more in this meeting report.

The post CARAMBA Meeting Report first appeared on CARAMBA.]]> The CARAMBA project presents its experiences, lessons learned and achievements in the development of an innovative CAR T-cell therapy for Multiple Myeloma treatment

Read more in this meeting report.

The post CARAMBA Meeting Report first appeared on CARAMBA.]]> The pioneering CARAMBA project is coming to an end https://www.caramba-cart.eu/caramba-project-end/?utm_source=rss&utm_medium=rss&utm_campaign=caramba-project-end Fri, 30 Jun 2023 10:43:18 +0000 https://www.caramba-cart.eu/?p=5807 On 30th June 2023, the EU-funded project CARAMBA is coming to an end, marking five years of challenges and successes in the mission to revolutionise multiple myeloma treatment and beyond. The ultimate goal of the CARAMBA project was to develop a new virus-free CAR-T therapy and demonstrate in a Phase I/IIa clinical trial the safety […]

The post The pioneering CARAMBA project is coming to an end first appeared on CARAMBA.]]> On 30th June 2023, the EU-funded project CARAMBA is coming to an end, marking five years of challenges and successes in the mission to revolutionise multiple myeloma treatment and beyond.

The ultimate goal of the CARAMBA project was to develop a new virus-free CAR-T therapy and demonstrate in a Phase I/IIa clinical trial the safety and efficacy of SLAMF7 CAR-T cells against multiple myeloma cells. In this innovative treatment approach, white blood cells of the myeloma patients are collected and equipped with a so-called “Chimeric Antigen Receptor” (CAR). The CAR acts like a sensor that detects the surface molecule SLAMF7 on myeloma cells and guides the white blood cells to specifically target and destroy these malignant cells. Currently, there is still no cure for multiple myeloma, a disease that affects more than 50,000 people in Europe every year. Therefore, there is a high clinical need for alternative treatments increasing not only the survival rate, but also patients’ quality of life.

Read more in the press release: CARAMBA_PR_2023

The post The pioneering CARAMBA project is coming to an end first appeared on CARAMBA.]]>